| icon | info | RA score |
|---|---|---|
 | They're Mutants, Not Zombies! Complete Papa's Palace of Pain in Story Mode | 1points |
 | Send More Paramedics! Complete Ballistic Trauma in Story Mode | 2points |
 | Step Right Up! Complete Carny in Story Mode | 3points |
 | Ticket to Ride Complete Scream Train in Story Mode | 4points |
 | Swamp Thing Complete The Fetid Waters in Story Mode | 5points |
 | Jailhouse Rock Complete Jailhouse Judgement in Story Mode | 5points |
 | Motherfucker! Complete Overkill in Story Mode | 10points |
 | Not Just a Cabbage Complete Papa's Palace of Pain in Director's Cut | 10points |
 | Malpractice Complete Ballistic Trauma in Director's Cut | 10points |
 | Freakshow Complete Carny in Director's Cut | 10points |
 | End of the Line Complete Scream Train in Director's Cut | 10points |
 | See Ya Later, Alligator Complete The Fetid Waters in Director's Cut | 10points |
 | Life Sentence Complete Jailhouse Judgement in Director's Cut | 10points |
 | Family Reunion Complete Overkill in Director's Cut | 25points |
 | Pocket Money Stockpile $10,000 in your wallet in Story Mode | 5points |
 | Filthy Rich Stockpile $10,000 in your wallet in Director's Cut Mode | 5points |
 | Director's Vision Complete Papa's Palace of Pain in Director's Cut with 90% accuracy or greater | 5points |
 | Surgical Precision Complete Ballistic Trauma with 90% accuracy or greater | 5points |
 | Carnival Sniper Complete Carny in Story Mode with 90% accuracy or greater | 5points |
 | Bullet Train Complete Scream Train with 90% accuracy or greater | 5points |
 | Swamp Marksman Complete The Fetid Waters with 90% accuracy or greater | 5points |
 | Prison Guard's Aim Complete Jailhouse Judgement with 90% accuracy or greater | 5points |
 | Mutant Hunter Complete Overkill with 90% accuracy or greater | 10points |
 | Not Even a Scratch Complete Overkill in Story Mode without dying | 10points |
 | Untouchable Complete any Director's Cut level without dying | 10points |
 | Gore-geous! Enter Goregasm for the very first time | 1points |
 | Ultimate Goregasm Achieve a 5-minute Goregasm | 5points |
 | Explosive Climax Defeat any boss while your Goregasm is active | 25points |
 | One Hundred Shades of Red Achieve a combo of 100 in any chapter | 5points |
 | S for Slaughter Achieve an "S" Rank after killing the chapter's boss | 25points |
 | Brain Salad Shoot 50 mutants in the head in a single chapter | 1points |
 | Shop Smart, Shop S-Mart Buy all weapons available from the Gun Shop | 10points |
 | Locked and Loaded Fully upgrade all weapons in the game to their maximum potential | 25points |
 | More Brains! Collect all the Golden Brains across all Director's Cut chapters | 50points |
 | Hero of the Day Save all civilians across all Director's Cut chapters | 25points |
 | Break a Leg Make 70 leg shots in a single chapter | 1points |
 | When There's No More Room in Hell... Eradicate a total of 2,000 mutants across all chapters | 10points |
 | Stick Around for the Sequel! Watch the whole end credits sequence without skipping | 1points |
 | I Scream, You Scream Complete Carny in Story Mode using only the AMS Magnum without dying | 3points |
 | Winner Winner, Mutant Dinner In the Money Shot II minigame, reach 60,000 points or greater | 5points |
 | Dead on Arrival In the Stayin' Alive minigame, kill 180 mutants or more | 5points |
 | Collateral Damage In the Victim Support minigame, reach 17,500 points or greater without killing any civilians | 5points |
 | Say Hello to My Little Friend! Kill 83 mutants while holding your gun Gangster Style in a single chapter | 1points |
