| icon | info | score |
|---|---|---|
| Another Piece of Cake Beat The Doctor Who Cloned Me campaign on Easy Difficulty unlocked Jan 15th, 2012 6:47 am | 20 | |
| Let's Rock Out Beat The Doctor Who Cloned Me campaign on Normal Difficulty unlocked Jan 15th, 2012 6:47 am | 30 | |
| Bloody Red Rover Kill 30 enemies with the moon rover unlocked Jan 15th, 2012 6:00 am | 10 | |
| Bubble Buster Kill 10 expanded enemies with melee attacks unlocked Jan 15th, 2012 5:33 am | 10 | |
| Heart to Heart Finish Doctor Proton unlocked Jan 7th, 2012 11:06 pm | 20 | |
| Threesome Kill 3 enemies within 3 seconds with the Impregnader unlocked Jan 7th, 2012 10:10 pm | 10 | |
| Sticky Bomb Like You! Put a Trip Mine on a live alien unlocked Jan 7th, 2012 5:33 pm | 10 | |
| Party Animal Drink all of the beers in the strip club unlocked Jan 7th, 2012 4:43 pm | 10 | |
| Downtown Barrel Beatdown Kill 10 aliens with tossed objects unlocked Jan 7th, 2012 4:11 pm | 15 | |
| Special Thanks Watch the credits all the way through unlocked Jan 7th, 2012 4:05 pm | 5 | |
| Gunslinger Carry the gold pistol through the whole SP campaign unlocked Jan 7th, 2012 3:54 pm | 50 | |
| Piece of Cake Complete the SP campaign on Easy Difficulty unlocked Jan 7th, 2012 3:54 pm | 20 | |
| Let's Rock Complete the SP campaign on Normal Difficulty unlocked Jan 7th, 2012 3:54 pm | 30 | |
| Beating the One-Eyed Worm Defeat the Energy Leech unlocked Jan 7th, 2012 3:16 pm | 35 | |
| Octacide Defeat the Octaking unlocked Jan 7th, 2012 3:11 am | 25 | |
| Fork the Pork Kill 6 aliens with the forklift unlocked Jan 5th, 2012 12:15 am | 10 | |
| I Need a Date Look at every page of a calendar unlocked Jan 2nd, 2012 2:36 am | 5 | |
| Freeze Well! Kill 15 frozen aliens unlocked Jan 2nd, 2012 2:34 am | 20 | |
| Dead Useful Kill 10 aliens with environmental explosives unlocked Jan 2nd, 2012 2:32 am | 15 | |
| A Good Dam Fight Defeat the Battlelord on the Hoover Dam unlocked Jan 2nd, 2012 2:22 am | 25 | |
| He's Got a Hologram! Use a Holoduke in SP unlocked Jan 2nd, 2012 1:25 am | 5 | |
| Road Rage Kill 15 aliens with the monster truck unlocked Jan 1st, 2012 4:27 am | 20 | |
| On the Noggin Kill 30 aliens with headshots unlocked Jan 1st, 2012 3:39 am | 25 | |
| Lots of Whacking Win a game of Alien Abortion in the strip club unlocked Dec 31st, 2011 12:16 am | 25 | |
| Not Bad for a Human Defeat the Alien Queen unlocked Dec 30th, 2011 11:54 pm | 40 | |
| Noms Eat 10 pieces of food during the SP campaign unlocked Dec 28th, 2011 1:48 am | 10 | |
| Turd Burglar Find and steal a piece of poo unlocked Dec 28th, 2011 1:31 am | 10 | |
| Trapper Kill 10 aliens with Trip Mines unlocked Dec 28th, 2011 12:53 am | 20 | |
| I Need a Towel Get hit by 10 Pregnator bombs unlocked Dec 27th, 2011 5:42 pm | 10 | |
| FBT Get knocked down 10 times unlocked Dec 27th, 2011 5:40 pm | 10 | |
| Hippy-Stomper Foot stomp 12 aliens unlocked Dec 27th, 2011 4:43 pm | 20 | |
| Nuclear Devastation Kill 250 aliens unlocked Dec 27th, 2011 5:54 am | 50 | |
| Pit Champion Defeat the Battlelord in Las Vegas unlocked Dec 27th, 2011 5:35 am | 25 | |
| Substance Abuser Drink beer while on steroids or vice versa in SP unlocked Dec 27th, 2011 1:23 am | 10 | |
| Judge, Jury, Executioner Execute 20 aliens unlocked Dec 27th, 2011 1:04 am | 20 | |
| Juiced Take steroids in SP unlocked Dec 27th, 2011 12:58 am | 5 | |
| Annihilation Kill 100 aliens unlocked Dec 27th, 2011 12:41 am | 40 | |
| Baron von Nukem Shoot down 20 alien fighters unlocked Dec 26th, 2011 11:49 pm | 20 | |
| Natural Disaster 3x Kill 3 aliens at once unlocked Dec 26th, 2011 11:48 pm | 10 | |
| Big Guns, Big Ships Blow up 5 enemy gunships or dropships unlocked Dec 26th, 2011 11:48 pm | 10 | |
| Extermination Kill 50 aliens unlocked Dec 26th, 2011 11:43 pm | 25 | |
| Flagon of Chuckles Drink a beer in SP unlocked Dec 26th, 2011 11:18 pm | 5 | |
| Nobody Likes a Whiner Knock out the talent at the talk show unlocked Dec 26th, 2011 10:56 pm | 5 | |
| One-Eyed Freak Defeat the Cycloid unlocked Dec 26th, 2011 10:40 pm | 10 | |
| Sunday, Black Sunday Shoot down the blimp above the stadium unlocked Dec 26th, 2011 10:36 pm | 5 | |
| Drawrings Doodle something on the whiteboard in SP unlocked Dec 26th, 2011 10:33 pm | 10 | |
| Duke Angry, Duke Smash! Kill 15 aliens with melee attacks while on steroids | 20 | |
| Bucket Head Find all 3 helmets in the SP campaign | 30 | |
| Companion Barrel Unlock the secret closet at the end of the Forkstop | 10 | |
| Pescaphobe Kill all the catfish in the underwater level | 10 | |
| Air-Duke Win air hockey with a score of 7-0 in the strip club | 30 | |
| Balls of Steel Earn a 1,000,000 pinball score in SP | 25 |
